MicroVue Helical Peptide EIA** Helical Peptide a1(I) 620-633

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產(chǎn)品名稱: MicroVue Helical Peptide EIA** Helical Peptide a1(I) 620-633

產(chǎn)品型號: 8022

產(chǎn)品展商: Quidel

產(chǎn)品文檔: 無相關(guān)文檔

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MicroVue Helical Peptide EIA** Helical Peptide a1(I) 620-633

MicroVue Helical Peptide EIA** Helical Peptide a1(I) 620-633 的詳細介紹

For Research Use Only. Not for use in diagnostic procedures.

The MicroVue Helical Peptide is a test to measure type I collagen helical peptide α1(I) 620-633 in urine, a marker for researching collagen degradation.

Type I collagen is degraded during bone resorption, releasing into circulation peptides of various molecular weights that are further degraded and/or released into urine. A peptide consisting of residues 620-633 derived from the helical region of the α1 chain was isolated from the urine of a patient with Paget's disease.

Features & Benefits

Feature	Benefit

Product Specifications

Product Spec Name	Product Spec Data
Format	ELISA
Test/kit	96 wells/plate
Sample type	Urine

Performance Characteristics

Method: Competitive
Analyte: Helical Peptide α1(I) 620-633
Specimen: Urine
Specimen Volume: 20 μL
LOD*: 8 μg/L
LLOQ*: 20.2 μg/L
HLOQ*: 2514 μg/L
Precision CVs within-run: 4%-8%
Precision CVs between-run: 7%-17%
Incubation Time: 19-25 Hours
Cross-reactivity: Helical peptide α1(I) 620-633 100% Intact collagen I, II, III, IV < 1% Homologous peptides (see Package Insert)

*LOD = Limit of Detection, LLOQ = Lower Limit of Quantification, HLOQ = Higher Limit of Quantification

About the Assay

Format

96-well microplate with reagents sufficient to test 40 samples in duplicate

Antibody Specificity

Helical peptide α1(I) 620-633; no reactivity with intact collagen types I, II, III, IV or mixtures of amino acids; 90% reactivity with α1(III) homologous peptide; no reactivity with α1(I) or α2(II) homologous peptides