Anti-NGAL (human) ABS 062-14

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產(chǎn)品名稱: Anti-NGAL (human) ABS 062-14

產(chǎn)品型號(hào): ABS 062-14

產(chǎn)品展商: Bioporto

產(chǎn)品文檔: 無相關(guān)文檔

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Anti-NGAL (human)

Anti-NGAL (human) ABS 062-14 的詳細(xì)介紹

Cat. No.: ABS 062-14B
Product name: Anti-NGAL (human)
Description: Mouse monoclonal antibody, biotinylated
Specificity: ABS 062-14 is specific for human NGAL (neutrophil gelatinase-associated lipocalin)
Immunogen: Human recombinant NGAL coupled to carrier?
Application: ELISA
Species reactivity (positive): Human
Species reactivity (negative): Not determined
Subclass: IgG2a/k
Gene ID: 3934
Clone number: 14
Epitope: Differs from those of HYB 211-01, the ABS 038 series of antibodies and ABS 062-33.
Content: 50 μL, 1 mg/mL +/- 15%. See Certificate of Analysis for details.
Purification: Biotinylated
Form: Liquid
Solvent: 0.01 M phosphate buffer, pH 7.4, with 0.14 M NaCl and 15 mM sodium azide
Storage: 4-8oC without exposure to light. No precautions necessary during handling.
Target: Neutrophil gelatinase-associated lipocalin (NGAL; also called lipocalin 2, siderocalin and neutrophil lipocalin) is a member of the lipocalin family of proteins which bind and transport small lipophilic molecules. NGAL is released by activated neutrophils and occurs as 25-kDa glycosylated single protein chain monomers, which form dimers and small amounts of higher oligomers, as well as complexes with matrix metalloproteinase 9 (MMP-9; gelatinase B). Low level expression of NGAL in a variety of epithelia may be increased in inflammation or cancers. Expression of NGAL in the kidney is dramatically increased by acute kidney injury.

Application 1: ELISA

When ABS 062-14 is used as biotinylated detection antibody with ABS 062-33 as capture antibody, the assay is specific for NGAL monomer, cross-reacting <1% with NGAL homodimer.
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The calibration curve of a sandwich assay for monomer human NGAL using ABS 062-33 as the capture antibody and ABS 062-14B as the biotinylated detection antibody.?(1).