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Biotin phosphoramidite (hydroxyprolinol)

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產品名稱: Biotin phosphoramidite (hydroxyprolinol)
產品型號: 22360 42360
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Biotin phosphoramidite (hydroxyprolinol) 22360 42360


Biotin phosphoramidite (hydroxyprolinol)  的詳細介紹

Biotin phosphoramidite (hydroxyprolinol)

Phosphoramidite
Cat. # Quantity Price Lead time
22360 250 mg  240.00$ in stock
 
42360 1 g  560.00$ in stock
 
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Non-nucleosidic modifier reagent for the synthesis of biotinylated oligos based on a hydroxyprolinol core. This phosphoramidite contains a dimethoxytrityl protective group for the purification of the resulting oligos on C18 cartridges, and reverse phase HPLC. This modifier reagent can be used to introduce biotin onto 5'-position, 3'-position (using universal CPG), and internal oligo sites.

This amidite does not require special condensation and deprotection conditions.

Biotin phosphoramidite (hydroxyprolinol)
Biotin phosphoramidite (hydroxyprolinol)
Biotin phosphoramidite (hydroxyprolinol)
Structure of biotin phosphoramidite
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ChemDraw format

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General properties

Appearance: white powder
Molecular weight: 959.18
Molecular formula: C51H71N6O8PS
Solubility: good in MeCN, DCM, THF
Quality control: NMR 1H, 31P, HPLC-MS (95%), functional testing in oligo synthesis
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS: Download

Oligo synthesis details

Coupling conditions: standard coupling, identical to normal nucleobases
Deprotection conditions: identical to protected nucleobases
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