Pyrene phosphoramidite dU
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產品名稱: Pyrene phosphoramidite dU
產品型號: 11460 21460 41460
產品展商: 其它品牌
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Pyrene phosphoramidite dU
11460 21460 41460
Pyrene phosphoramidite dU
的詳細介紹
Pyrene phosphoramidite dU
Oligonucleotide synthesis Phosphoramidite Pyrene
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Cat. #
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Quantity
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Price
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Lead time
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Buy this product
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11460
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100 mg
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150.00$
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21 days
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21460
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250 mg
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320.00$
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21 days
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41460
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1 g
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from $800" src="https://www.lumiprobe.com/images/icon-truck-small.svg" data-original-title="" title="" style="box-sizing:border-box;vertical-align:middle;" /> 880.00$
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21 days
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Bulk inquiry 
Pyrene is polycyclic aromatic hydrocarbon which is well-known for its ability to intercalate into DNA. Pyrene features intense blue fluorescence. Its parameters depend strongly on fluorophore microenvironment. Therefore, fluorescence spectra of pyrene are used for the extraction of structural information about site surrounding pyrene. Two pyrenes in close proximity usually form excimers easily detectable by excimer fluorescence. Pyrene can also be a FRET donor to other fluorophores such as perylene.
With this phosphoramidite, pyrene can be introduced into DNA by means of automated synthesis. This pyrene phosphoramidite contains hydrocarbon moiety rigidly attached to deoxyuridine. This reagent allows to attach pyrene fragment to 5', internal, or 3' position (using universal support).
This amidite requires no special handling, coupling, or deprotection conditions. Recommended diluent for it is acetonitrile.
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ChemDraw format
Absorption and emission spectra of pyrene fluorophore
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General properties
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Appearance:
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yellowish foam
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Molecular weight:
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955.04
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Molecular formula:
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C57H55N4O8P
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Solubility:
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good in dichloromethane and acetonitrile
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Quality control:
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NMR 1H (95%), 31P, HPLC-MS
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Storage conditions:
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Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
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MSDS:
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Download
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Spectral properties
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Excitation maximum, nm:
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260; 282; 365; 392
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ε, L?mol?1?cm?1:
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12600; 21900; 16000; 14200
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Emission maximum, nm:
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460
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Fluorescence quantum yield:
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~0.1
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