TA100 - S.typhimurium Tester Strain for Ames Test 

• for the detection of genotoxic chemicals according to OECD 471 
• for the detection of genotoxic impurities according to ICH M7 Guideline
• for testing waste or surface water according to ISO ISO 11350:2012.
• for the screening of chemicals, pharmaceuticals or cosmetics in a miniaturized assay system (Ames MPF)

Characteristics

• Mutation: hisG46
• Type: Base Pair Substitution  
• Target: GGG
• rfa Mutation: defective lipopolysaccharide (LPS) layer
• uvrB Mutation: Eliminates the accurate excision repair mechanism
• pKM101 R-Factor Plasmid: Enhances chemical and UV-induced mutagenesis, Ampicilline Resistance
• Shipment with ice bricks at room temperature from Germany

Safety

The strains of Salmonella typhimurium and Escherichia coli are classified under the lowest level of risk, groupe 1 in Switzerland, Biostoff S1 in Germany, ... They are considered as non-GMOs because they can be constructed by self-cloning or are naturally occurring bacterial strains. They do not disturb the biological diversity.