BCAPC-1080 Bovine Activated Protein C
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產品名稱: BCAPC-1080 Bovine Activated Protein C
產品型號: BCAPC-1080
產品展商: 其他品牌
產品文檔: 無相關文檔
簡單介紹
Activated Protein C
PRODUCT INQUIRY
Inactivation of Factor Va by Activated Protein C (APC)
Proteolytic inactivation of factor Va by APC is represented, where: PS=protein S, PCPS=phospholipid vesicles (or cellular surface) and Ca++=calcium ions. The inactivation of factor Va to form factor Vai results from proteolysis of the factor Va heavy chain (94K) at three specific sites by APC (solid arrow
BCAPC-1080 Bovine Activated Protein C
的詳細介紹
Activated Protein C
PRODUCT INQUIRY
Inactivation of Factor Va by Activated Protein C (APC)
Proteolytic inactivation of factor Va by APC is represented, where: PS=protein S, PCPS=phospholipid vesicles (or cellular surface) and Ca++=calcium ions. The inactivation of factor Va to form factor Vai results from proteolysis of the factor Va heavy chain (94K) at three specific sites by APC (solid arrows) (1,2). The location of these cleavage sites in the factor Va heavy chain are as follows: (human: R306, R506, & R679) and (bovine: R306, R505, & R662). Complete inactivation of the cofactor molecule requires cleavage at the Arginine-306 position. Cleavage at Arginine-306 by activated protein C occurs only in the presence of membrane, and requires prior cleavage of the heavy chain at Arginine-505. Proteolysis of the factor Va light chain by APC occurs only in the bovine molecule and is not required for inactivation (dashed arrow).
HCAPC-0080 Human Activated Protein C Pricing: Please Inquire SAMPLE DATA SHEET | SAFETY DATA SHEET
Size 50 μg
Formulation 50% (vol/vol) Glycerol/H2O
Storage -20°C
Purity >95% by SDS-PAGE
Activity Determination Chromogenic Assay
Shelf Life (properly stored) 12 months
HCAPC-DEGR Human Activated Protein C - DEGR (active site blocked) Pricing: Please Inquire SAFETY DATA SHEET
Size 50 μg
Formulation 20 mM Tris, 150 mM NaCl, pH 7.4
Storage -80°C
Purity >95% by SDS-PAGE
Activity Determination Chromogenic Assay
Shelf Life (properly stored) 12 months
BCAPC-1080 Bovine Activated Protein C Pricing: Please Inquire SAFETY DATA SHEET
Size 50 μg
Formulation 50% (vol/vol) Glycerol/H2O
Storage -20°C
Purity >95% by SDS-PAGE
Activity Determination Chromogenic Assay
Shelf Life (properly stored) 12 months
BCAPC-DEGR Bovine Activated Protein C - DEGR (active site blocked) Pricing: Please Inquire SAFETY DATA SHEET
Size 50 μg
Formulation 20 mM Hepes, 150 mM NaCl, pH 7.4
Storage -80°C
Purity >95% by SDS-PAGE
Activity Determination Chromogenic Assay
Shelf Life (properly stored) 12 months
